Dr. Mazen Shaheen

Peripheral Vascular Disease

What is Peripheral Vascular Disease (PVD)?

Peripheral Vascular Disease (PVD) is a disorder of the blood vessels, a circulatory condition that occurs when blood flow to your 4 limbs(typically your arms and legs) is reduced.
What is the main cause of peripheral artery disease? This happens due to narrowed or blocked blood vessels not just in arms and legs, PVD can affect any blood vessel located outside of the heart. This includes arteries, veins, and lymphatic vessels. When these blood vessels are narrowed or blocked, the organs they supply, even the brain, may not receive adequate blood flow, leading to various health issues.

Is PVD the Same as PAD?

Peripheral Artery Disease (PAD) is a specific type of PVD that affects the arteries. It occurs when these arteries become narrowed or blocked, reducing blood flow to the limbs. While all PAD is considered PVD, not all PVD is PAD. Other conditions like chronic venous insufficiency (CVI) and deep vein thrombosis (DVT) are also types of PVD but affect the veins, not the arteries

Peripheral Vascular Disease (PVD) in Dubai

The prevalence of peripheral vascular disease (PVD) in Dubai is a growing concern. Dubai ‘s diverse population, including expatriates from various regions with different health profiles, contributes to the complexity of PVD cases in the country. Early detection and proper management of PVD are crucial for preventing severe complications and improving the quality of life for affected individuals.
Given the growing awareness of cardiovascular health and the increasing focus on preventive care in Dubai, early detection and management of PAD are crucial for improving the overall health and well-being of the population.

What Causes Peripheral Vascular Disease?

The primary cause of PVD is atherosclerosis, a condition where plaque (a build-up of fatty substances) forms inside your arteries, decreasing the oxygen and nutrients sent to the tissue. As this plaque accumulates, it narrows the arteries, reducing blood flow to your limbs. Other factors, such as blood clots or inflammation, can also contribute to PVD.

Other causes of PVD may include:

  • Arm or leg injuries
  • Infections
  • Irregular anatomy
  • Muscles or ligaments

Who is at Risk for Peripheral Vascular Disease?

Several factors increase your risk of developing PVD, including

Age: older adults are at higher risk

Smoking

Diabetes

High blood pressure

High cholesterol levels

Obesity

Sedentary lifestyle

Family history of PVD or other circulatory conditions

What are the Symptoms of Peripheral Vascular Disease?

What are the signs of vascular disease? Symptoms of PVD can vary depending on the severity of the condition. Common symptoms include

The most common symptom is pain, which becomes worse as the circulation is more limited.

Leg cramping, especially when walking

Numbness or tingling in the legs or feet

Weak pulses in the legs or feet

Cold extremities

Skin sores that heal slowly or not at all

Changes in skin color or texture

Erectile dysfunction (in men)

What Does Peripheral Vascular Disease Look Like in The Legs?

Peripheral vascular disease (PVD) can manifest in various ways in the legs. Common signs include

Skin changes

Shiny, hairless skin, discoloration, or sores that don’t heal.

Swelling

Accumulation of fluid in the legs.

Varicose veins

Enlarged, twisted veins.

Leg ulcers

Open sores that are difficult to heal.

Color changes

The legs may appear pale, blue, or reddish depending on the blood flow.

Stages of Peripheral Artery Disease (PAD)

To assess the severity of peripheral artery disease (PAD), healthcare providers use classification systems to stage the condition. Two common systems are the Fontaine and Rutherford classifications.

The Fontaine stages, a simpler system, categorize PAD as follows

Stage I

Asymptomatic – No symptoms present.

Stage IIa

Mild claudication – Leg pain occurs during exercise.

Stage IIb

Moderate to severe claudication – Leg pain significantly limits daily activities.

Stage III

Ischemic rest pain – Leg pain occurs even while resting.

Stage IV

Tissue loss or gangrene – Severe lack of blood flow leading to tissue damage.

General FAQs

You should contact your healthcare provider if you experience any symptoms of PVD. Prompt diagnosis and treatment are essential to prevent complications.

Your healthcare provider will conduct a physical exam and may order tests to diagnose PVD, including:

  • Ankle-brachial index (ABI): Compares blood pressure in your arms and ankles.
  • Doppler ultrasound: Uses sound waves to assess blood flow.
  • Angiography: Uses X-ray imaging to visualize blood vessels.

If left untreated, PVD can lead to serious complications, such as:

  • Peripheral arterial disease (PAD): A more severe form of PVD
  • Critical limb ischemia (CLI): Severely reduced blood flow to the limbs
  • Aneurysm: A bulge in a blood vessel wall
  • Heart attack or stroke
  • Gangrene: Tissue death due to lack of blood flow

When lifestyle modifications and medications are not sufficient to manage PVD, minimally invasive or surgical treatments may be necessary. These procedures aim to restore blood flow and prevent disease progression to the affected limbs:

  • Angioplasty and Stenting: A minimally invasive procedure involving the insertion of a thin tube (catheter) with a balloon at its tip into the blocked artery. The balloon is inflated to widen the artery, and a stent (a small, mesh tube) is often deployed to prevent re-narrowing.
  • Atherectomy: This procedure employs a specialized device to remove plaque buildup from the artery walls, improving blood flow.
  • Bypass Surgery: A more invasive procedure that involves creating new pathways for blood to bypass blocked areas. This is typically performed when multiple blockages are present or when angioplasty and stenting are not feasible.

While there’s no cure for peripheral artery disease (PAD), its progression can often be slowed, and in some cases, its symptoms are reversed. By adopting a heart-healthy lifestyle, including regular exercise, a balanced diet, and managing conditions like diabetes and high blood pressure, individuals with PAD can improve blood flow and reduce symptoms. Early detection and treatment are crucial for preventing the disease from worsening. It’s essential to consult with a healthcare professional for personalized guidance and management

Many cases of PVD can be prevented or managed through lifestyle changes. These include:
  • Quitting smoking
  • Regular exercise
  • Maintaining a healthy weight
  • Eating a balanced diet
  • Managing blood pressure and cholesterol levels
  • Regular check-ups

PAD and Amputation

In severe cases of peripheral artery disease where blood flow to the limbs becomes critically compromised, amputation may become a last choice. This drastic measure is typically considered when other treatment options, such as angioplasty, bypass surgery, or medication, have failed to restore adequate blood flow.

Critical limb ischemia (CLI) is a severe stage of PAD that significantly increases the risk of amputation. CLI occurs when the blood supply to the limbs is so reduced that it cannot meet the basic metabolic needs of the tissue. This leads to tissue damage and potentially life-threatening infections. Preventing amputation is a primary goal in PAD management. Early detection, aggressive risk factor management, and timely intervention can significantly reduce the risk of limb loss. Contact a vascular specialist or cardiologist at the earliest sign of PVD symptoms to initiate prompt diagnosis and treatment.

To read more about PAD, visit this link.

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